β-Elemonic acid
CAS No. : 28282-25-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $90 | In-stock |
| 10mg | $145 | In-stock |
| 25mg | $260 | In-stock |
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| Cat. No. : | HY-N2454 |
| M.Wt: | 454.68 |
| Formula: | C30H46O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C);H2O : < 0.1 mg/mL |
β-Elemonic acid is a triterpene isolated from Boswellia carterii. β-Elemonic acid induces cell apoptosis, reactive oxygen species (ROS) and COX-2 expression and inhibits prolyl endopeptidase. β-Elemonic acid exhibits anticancer and anti-inflammatory effects[1][2].
In Vitro: β-elemonic acid (1, 3, 10, 20 µM; 24 hours) strongly induces human A549 lung cancer cell apoptosis in a dose- and time-dependent manner[1].
β-elemonic acid (1, 3, 10, 20 µM; 24 hours) exerts potent cytotoxic effects on human NSCLC A549 cells in a dose-dependent manner. The IC50 value following a 24-h exposure to β-elemonic acid was 6.92 µM[1].
β-elemonic acid (20 µM; 24 hours) results in a cell percentage of 58.01% in the G0/G1 phase[1].
β-elemonic acid (1, 3, 10, 20 µM; 24 hours) inhibits phosphorylation of p42/44, MAPK/JNK and p38 in the A549 cells[1].
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