Etidronic acid


CAS No. : 2809-21-4

(Synonyms: Etidronate; HEDPA; HEDP)

2809-21-4
Price and Availability of CAS No. : 2809-21-4
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Cat. No. : HY-B0302
M.Wt: 206.03
Formula: C2H8O7P2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic)
Introduction of 2809-21-4 :

Etidronic acid (Etidronate) is an orally and intravenously active bisphosphonate. Etidronic acid inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid has anticancer activity. Etidronic acid is a chelating agent and can be used to remove heavy metal in water[1][2][3][4]. In Vitro: Etidronic acid (Etidronate) (10 mM, 24 h) shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells[3].
Etidronic acid (100 nM, 24 h) induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy[5].

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