BMS 310705
CAS No. : 280578-49-6
(Synonyms: 21-Aminoepothilone B)
| Size | Price | Stock |
|---|---|---|
| 1mg | $800 | In-stock |
| 5mg | $2000 | In-stock |
| 10mg | $3300 | In-stock |
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| Cat. No. : | HY-107020 |
| M.Wt: | 522.70 |
| Formula: | C27H42N2O6S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, renal, bladder, and lung carcinoma. BMS 310705 induces significant apoptosis via mitochondrial-mediated pathway[1].
In Vitro: BMS 310705 (0.01-0.5 μM; 1 h) induces cell apoptosis in OC-2 cells[1].
BMS 310705 (0.5 μM; 1 h) increases the activity of caspase-9 and -3, and leads to cytochrome c release[1].
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