S 1360
CAS No. : 280571-30-4
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| Cat. No. : | HY-12108 |
| M.Wt: | 313.28 |
| Formula: | C16H12FN3O3 |
| Purity: | >98 % |
| Solubility: |
S 1360 is a potent and selective inhibitor of HIV-1 integrase. S 1360 inhibits the catalytic activity of purified integrase ( IC50: 20 nM). The EC50, and CC50 of S 1360 in MTT assay (MT-4 cells infected with HIV-1 IIIB) are 200 nM and 12 μM, respectively. S 1360 has antiviral activity against both X4 tropic and R5 tropic strains, as well as NRTI, NNRTI and PI drug-resistant variants[1].
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