Gardenin B
CAS No. : 2798-20-1
| Size | Price | Stock |
|---|---|---|
| 1mg | $96 | In-stock |
| 5mg | $202 | In-stock |
| 10mg | $343 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-N6037 |
| M.Wt: | 358.34 |
| Formula: | C19H18O7 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
Gardenin B is a methoxyflavone compound and an inhibitor of USP7, ODC (IC50: 6.24 μg/mL), and Cathepsin D (IC50: 5.61 μg/mL). Gardenin B exhibits antioxidant and antitumor activities. Gardenin B shows IC50 values of 8.87 and 10.59 μg/mL for DPPH and NO scavenging, respectively, and also possesses ferric ion reducing ability. Additionally, Gardenin B can inhibit tumor cell proliferation, induce cell cycle arrest and apoptosis. Gardenin B can be used in cancer research[1][2][3]. In Vitro:Gardenin B (0-100 μM; 0-72 h) inhibits the growth of leukemia cell lines (with IC50 values of 1.6 and 3.0 μM for HL-60 and U-937, respectively), and induces cell cycle arrest, apoptosis, and production of ROS[1].
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