Vapitadine (hydrochloride)
CAS No. : 279253-83-7
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| Cat. No. : | HY-14939A |
| M.Wt: | 369.29 |
| Formula: | C17H22Cl2N4O |
| Purity: | >98 % |
| Solubility: |
Vapitadine hydrochloride (Compound 3a) is a selective, orally active and nonsedating antihistamine agent, which exhibits a good binding affinity with human cloned histamine H1 receptor with a Ki of 19 nM. Vapitadine hydrochloride decreases the histamine-induced lethality (ED50 is 0.056-1.2 mg/kg), antagonizes the cutaneous reactions to histamine (ED50 is 0.51-1.4 mg/kg) in rats[1].
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