Uridine-5'-diphosphate (disodium salt)
CAS No. : 27821-45-0
(Synonyms: UDP (disodium salt))
| Size | Price | Stock |
|---|---|---|
| 100mg | $20 | In-stock |
| 1g | $22 | In-stock |
| 5g | $68 | In-stock |
| 10g | $118 | In-stock |
| 25g | $267 | In-stock |
| 50 g | Get quote | |
| 100 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-W010832 |
| M.Wt: | 448.12 |
| Formula: | C9H12N2Na2O12P2 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : < 1 mg/mL |
Uridine-5'-diphosphate (UDP) disodium salt is an important nucleotide made of uracil, ribose, and a pyrophosphate group. Uridine-5'-diphosphate disodium salt is a potent, selective human P2Y6 receptor native agonist (EC50 = 300 nM; pEC50 = 6.52). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis[1][2].
IC50 & Target:EC50: 300 nM (P2Y6)[1]
pEC50: 6.52 (P2Y6)[1]
In Vitro:Uridine-5'-diphosphate (100 μM; 15 min) disodium salt significantly induces microglial CCL2 and CCL3 mRNA expression[2].
Uridine-5'-diphosphate (100 μM; 3 h) disodium salt induces chemokine expression in microglia[2].
Uridine-5'-diphosphate (100 μM; 0.5-12 h) induces expression of mRNA encoding CCL2 and CCL3 within 30 min, and such expression reaches maximal levels at 1 h, returning to basal levels at 3-12 h[2].
Uridine-5'-diphosphate (10-1000 μM; 3 h) induces a concentration-dependent increase in the expression of chemokines at both the mRNA and protein level[2].
Uridine-5'-diphosphate (10-1000 μM; 3 h) induces activation of NFATc1 and NFATc2 in microglia[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Uridine-5'-diphosphate (disodium salt)
- Cat. No.:
- HY-W010832
- Quantity:
Your information is safe with us.