(Rac)-WAY-161503 (hydrochloride)


CAS No. : 276695-22-8

276695-22-8
Price and Availability of CAS No. : 276695-22-8
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Cat. No. : HY-103138
M.Wt: 308.59
Formula: C11H12Cl3N3O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 276695-22-8 :

(Rac)-WAY-161503 hydrochloride is a potent, selective, high affinity 5-HT2C receptor agonist with a Ki of 4 nM and an EC50 of 12 nM. (Rac)-WAY-161503 hydrochloride displays higher affinity for 5-HT2C than 5-HT2A and 5-HT2B receptors. (Rac)-WAY-161503 hydrochloride has anti-obesity and antidepressant effects[1][2]. In Vivo: (Rac)-WAY-161503 (3-30 mg/kg; i.p.; male C57BL/6J mice) hydrochloride dose-dependently decreases locomotor activity, an effect that is blocked by the 5-HT2C/2B antagonist SER-082[1].

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