(Z)-9-Tricosene

(Z)-9-Tricosene (cis-9-Tricosene) is an insect pheromone found in dipteran flies. (Z)-9-Tricosene has multiple functions as a sex pheromone, aggregation pheromone and aphrodisiac pheromone, and mediates insect behaviors such as attraction, oviposition and mating via antennal receptors (e.g., the Or7a receptor). (Z)-9-Tricosene can be used in studies related to insecticides and insect chemical ecology^[1][2][3][4]. In Vitro:(Z)-9-Tricosene (0.1 μg/μl; 8 min) induces strong electrophysiological responses in excised first leg tarsi of sexually receptive female Pholcus beijingensis, with a mean EAG amplitude of 0.223 mV^[3].
(Z)-9-Tricosene (0.001-0.01 mg) used in GC-MS calibration reveals a mean titre of 0.114 mg of (Z)-9-tricosene per mate-searching male Pholcus beijingensis body extract^[3]. In Vivo:(Z)-9-Tricosene (10^-5-10^-3 V) is a potent aggregation pheromone of Drosophila melanogaster, which induces dose-dependent attraction^[1].
(Z)-9-Tricosene regulates oviposition site selection in female Drosophila melanogaster by guiding egg-laying to sites where this pheromone has been deposited^[1].
Addition of (Z)-9-Tricosene (content: 0.049%; free feeding; 60-minute no-choice feeding assay) to the diet has no effect on methomyl-induced mortality in methomyl-susceptible or resistant Musca domestica strains in no-choice laboratory assays^[2].
(Z)-9-tricosene (1 μg; air exposure) acts as an aphrodisiac stimulant for Pholcus beijingensis, reduces the courtship duration of males, and thus promotes faster mating with sexually receptive females^[3].
(Z)-9-tricosene (1 mg; air-exposed) reduces predatory behavior, decreases prey capture probability, and lowers the number of captured prey in food-deprived female Pholcus beijingensis spiders^[3].
(Z)-9-tricosene (0.01-1 mg; air exposure) exhibits no attractive activity towards sexually receptive female Pholcus beijingensis in dual-choice behavioral assays^[3].
(Z)-9-tricosene (0.25-25 μg/μl; applied to filter paper in the experimental arena) exhibits repellent effects on Lucilia sericata larvae at low concentrations, while no behavioral effects are observed at high concentrations^[4].
(Z)-9-tricosene (0.25-25 μg/μl; applied to filter paper placed in the experimental arena) attracts Calliphora vomitoria larvae and increases their crawling speed at high concentrations, while no behavioral effects are observed at low concentrations^[4].