Deoxyneocryptotanshinone


CAS No. : 27468-20-8

27468-20-8
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Cat. No. : HY-N3734
M.Wt: 298.38
Formula: C19H22O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 27468-20-8 :

Deoxyneocryptotanshinone, a natural tanshinone, is a high affinity BACE1 (Beta-secretase) inhibitor with an IC50 value of 11.53 μM. Deoxyneocryptotanshinone shows a promising dose-dependent inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 133.5 μM. Deoxyneocryptotanshinone can be used for Alzheimer's disease research[1][2]. IC50 & Target:IC50: 11.53 μM (BACE1)[1] and 133.5 μM (PTP1B)[2]

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