A-620223
CAS No. : 272769-49-0
| Size | Price | Stock |
|---|---|---|
| 100mg | $2174 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-10615 |
| M.Wt: | 286.37 |
| Formula: | C16H22N4O |
| Purity: | >98 % |
| Solubility: |
A-620223 is a PARP-1 inhibitor with a Ki of 8 nM against PARP-1 and EC50 of 3 nM in a whole cell assay. A-620223 demonstrates good in vivo efficacy in a B16F10 subcutaneous murine melanoma model in combination with Temozolomide (TMZ) (HY-17364) and in an MX-1 breast xenograph model in combination with Cisplatin (HY-17394). A-620223 can be used for the studies of melanoma and breast cancer[1]. In Vivo:A-620223 (1-25 mg/kg, s.c., successive administration for 7-14 days) demonstrates excellent potentiation of two cytotoxic agents, Temozolomide and Cisplatin, in both a mouse melanoma and a breast cancer model[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- A-620223
- Cat. No.:
- HY-10615
- Quantity:
Your information is safe with us.