4-Butyl-alpha-agarofuran


CAS No. : 272126-07-5

(Synonyms: Buagafuran; Buagarofuran)

272126-07-5
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10mg $80 In-stock
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Cat. No. : HY-19496
M.Wt: 262.43
Formula: C18H30O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 272126-07-5 :

4-Butyl-alpha-agarofuran (AF 5) is an anxiolytic and antidepressant agent. 4-Butyl-alpha-agarofuran a α-agarofuran derivative that can be isolated from Gharu-wood. 4-Butyl-alpha-agarofuran can be used for the research of neurological disease research[1]. In Vitro:4-Butyl-alpha-agarofuran (2 mg) is completely metabolized in 100 min to the hydroxy derivative I and carbonyl derivative II in human liver microsome incubation system[2]. In Vivo:4-Butyl-alpha-agarofuran (0.5-10 mg/kg; i.p., once) shows antianxiety effects in a social interaction test and the serotonin (5-HT) levels of striatum, cortex, and midbrain are significantly decreased[1].

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