Polydatin
CAS No. : 27208-80-6
(Synonyms: Piceid)
| Size | Price | Stock |
|---|---|---|
| 50mg | $30 | In-stock |
| 100mg | $42 | In-stock |
| 200mg | $58 | In-stock |
| 500mg | $92 | In-stock |
| 1g | $130 | In-stock |
| 5g | $390 | In-stock |
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| Cat. No. : | HY-N0120A |
| M.Wt: | 390.38 |
| Formula: | C20H22O8 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 29 mg/mL;H2O : 0.1 mg/mL (ultrasonic) |
Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses.
IC50 & Target:NF-κB, Autophagy
In Vitro: Polydatin protects cerebral cells from ischemic damages via improvement of microcirculation and inhibition of platelet aggregation. In addition, polydatin inhibits ICAM-1 expression in endothelial cells stimulated by lipopolysaccharide; it also attenuates adhesion between white blood cells and endothelial cells[1].
Polydatin inhibits cancer cell proliferation and cell cycle progression[4].
Polydatin induces ER stress-driven cell death[4].
In Vivo: Polydatin could significantly increase the activity of SOD and the heart rate, attenuate myocardial pathological damage, decrease MDA content, slightly increase arterial pressure and GSH-Px activity, reduce intervals of QRS, QT and ST, and lower FFA content[2].
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