Cefazolin (sodium)


CAS No. : 27164-46-1

(Synonyms: Cephazolin (sodium))

27164-46-1
Price and Availability of CAS No. : 27164-46-1
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100mg $35 In-stock
500mg $85 In-stock
1g $120 In-stock
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Cat. No. : HY-B1078
M.Wt: 476.49
Formula: C14H13N8NaO4S3
Purity: >98 %
Solubility: H2O : ≥ 100 mg/mL;DMSO : 100 mg/mL (ultrasonic)
Introduction of 27164-46-1 :

Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research[1]. Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD)[2]. In Vitro: Cefazolin sodium (0-300 μg/ml; 6 or 24 h) has a direct anti-inflammatory effect on C8-B4 cells stimulated by lipopolysaccharide[2].
Cefazolin sodium (0-400 μM; 72 h) treatment inhibits IL-2, IL-4 and IL-15-induced cell proliferation[3].
Cefazolin sodium (0-400 μM; 30 min) treatment inhibits IL-2, IL-4, IL-15 and IL-21-stimulated JAK3 phosphorylation[3]. In Vivo: Cefazolin sodium (Subcutaneous injection; 300-500 mg/kg; once daily; 5 d) treatment improves learning and memory in mice after surgery[2].

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