AP22408
CAS No. : 268741-43-1
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| Cat. No. : | HY-125064 |
| M.Wt: | 665.61 |
| Formula: | C30H41N3O10P2 |
| Purity: | >98 % |
| Solubility: |
AP22408 is a nonpeptide inhibitor against Src SH2 with an IC50 value of 0.3 μM. AP22408 inhibits rabbit osteoclast-mediated resorption of dentine, exhibits bone-targeting properties based on a hydroxyapatite adsorption assay and demonstrates in vivo antiresorptive activity in a parathyroid hormone-induced rat model. AP22408 is proming for rasearch of osteoporosis and other bone-related diseases such as Paget’s disease, osteolytic bone metastasis and hypercalcemia associated with malignancy[1].
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