D-Sedoheptulose 7-phosphate


CAS No. : 2646-35-7

2646-35-7
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Cat. No. : HY-113206
M.Wt: 290.16
Formula: C7H15O10P
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 2646-35-7 :

D-Sedoheptulose 7-phosphate is a common precursor for the heptoses of septacidin (group III) and hygromycin B (group IV). D-Sedoheptulose 7-phosphate can be converted to NDP-heptoses through similar biosynthetic pathways in those compounds [1]. IC50 & Target: IC50: heptoses precursor[1] In Vitro: Sedoheptulose 7-phosphate can be converted to ADP-l-glycero-β-d-manno-heptose by SepB, SepL, and SepC, it involves in ADP-sugar in microbial natural product biosynthesis[1].
SepB is an S-7-P isomerase, SepL involves in the biosynthesis of heptoses of the core region of?E. coli?LPS, and they catalyze a four-reaction relay converting S-7-P into ADP-d-glycero-β-d-manno-heptose [1].
Septacidin and its analogs are potential anticancer and pain-relief agents[1].
Hygromycin B is an anthelmintic agent practically used in swine and poultry farming[1].

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