| Size | Price | Stock |
|---|---|---|
| 318.01 μM * 5 mL in Methyl acetate | $1600 | Get quote |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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| Cat. No. : | HY-116003 |
| M.Wt: | 314.46 |
| Formula: | C18H34O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
12,13-DiHOME is a stimulator of Brown adipose tissue (BAT), as well as a thermogenic lipokine that activates BAT in response to cold. (±)12,13-DiHOME activates BAT fuel uptake and enhances cold tolerance, via promoting the translocation of the FA transporters FATP1 and CD36 to the cell membrane. (±)12,13-DiHOME can be used for research of metabolic disorders[1].
In Vivo: 12,13-DiHOME (1 μg/kg; retro-orbitally injection; once daily for 2 weeks) acutely decreases levels of serum triglycerides in mice with high-fat diet model, and increases BAT uptake to defend cold[1].
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