12,13-DiHOME


CAS No. : 263399-35-5

263399-35-5
Price and Availability of CAS No. : 263399-35-5
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318.01 μM * 5  mL in Methyl acetate $1600 Get quote
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Cat. No. : HY-116003
M.Wt: 314.46
Formula: C18H34O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 263399-35-5 :

12,13-DiHOME is a stimulator of Brown adipose tissue (BAT), as well as a thermogenic lipokine that activates BAT in response to cold. (±)12,13-DiHOME activates BAT fuel uptake and enhances cold tolerance, via promoting the translocation of the FA transporters FATP1 and CD36 to the cell membrane. (±)12,13-DiHOME can be used for research of metabolic disorders[1]. In Vivo: 12,13-DiHOME (1 μg/kg; retro-orbitally injection; once daily for 2 weeks) acutely decreases levels of serum triglycerides in mice with high-fat diet model, and increases BAT uptake to defend cold[1].

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