Ethamsylate
CAS No. : 2624-44-4
(Synonyms: Etamsylate)
| Size | Price | Stock |
|---|---|---|
| 1g | $30 | In-stock |
| 5g | $100 | In-stock |
| 10g | $160 | In-stock |
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| Cat. No. : | HY-B1074 |
| M.Wt: | 263.31 |
| Formula: | C10H17NO5S |
| Purity: | >98 % |
| Solubility: | DMSO : 120 mg/mL (ultrasonic);H2O : 50 mg/mL (ultrasonic) |
Ethamsylate (Etamsylate) is an orally active anti-hemorrhagic compound. Ethamsylate inhibits biosynthesis and action of prostaglandins. Ethamsylate has the potential to maintain early hemostasis as well as restores capillary resistance. Ethamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis.[1][2][3].
In Vitro:Ethamsylate (480 μM, 30 mim) prolongs lifetime of neutrophils[1].
Ethamsylate (0-100 μM, 3-8 h) inhibits migration and tubulogenesis on matrigel in endothelial cells[3].
Ethamsylate (0-100 μM, 48 h), inhibits the signaling of FGF/FGFR, decreases phosphorylation Levels of AKT and Erk1/2[3].
In Vivo:Ethamsylate (100 mg/kg, p.o., twice a day, three days) attenuates mutilated secondary pathogenesis and exhibits a neuroprotective role in mice of spinal cord injury[4].
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