SB-269970 (hydrochloride)
CAS No. : 261901-57-9
(Synonyms: SB-269970A)
| Size | Price | Stock |
|---|---|---|
| 5mg | $112 | In-stock |
| 10mg | $174 | In-stock |
| 25mg | $371 | In-stock |
| 50mg | $576 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-15370A |
| M.Wt: | 388.95 |
| Formula: | C18H29ClN2O3S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 30 mg/mL;H2O : 10 mg/mL (ultrasonic;warming;heat to 60°C) |
SB-269970 hydrochloride is a potent, selective and brain-penetrant 5-HT7 receptor antagonist with a pKi of 8.3. SB-269970 hydrochloride exhibits >50-fold selectivity against other 5-HT receptors[1][2]. IC50 & Target: pKi: 8.3 (5-HT7 receptor)[1] In Vivo: SB269970 hydrochloride (SB-269970A) (3-30 mg/kg; i.p.; once) significantly blocks amphetamine and ketamine-induced hyperactivity[2].
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