Otilonium (bromide)
CAS No. : 26095-59-0
(Synonyms: Octylonium bromide; SP63)
| Size | Price | Stock |
|---|---|---|
| 10mg | $28 | In-stock |
| 25mg | $40 | In-stock |
| 50mg | $55 | In-stock |
| 100mg | $80 | In-stock |
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| Cat. No. : | HY-B0499A |
| M.Wt: | 563.57 |
| Formula: | C29H43BrN2O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
Otilonium bromide (OB) is an orally active mAChR inhibitor and smooth muscle relaxant which can interfere with the mobilization of calcium in intestinal smooth muscle, OB can be used for research of irritable bowel syndrome[1][2][3].
In Vitro:Otilonium bromide (10 nM-100 μM) inhibits acetylcholine-induced human colonic crypt calcium signals in a dose dependent manner with an IC50 of 880 nM[2].
Otilonium bromide (30 µM) inhibits Ca2+ uptake in bovine chromaffin cells[3].
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