Lasalocid


CAS No. : 25999-31-9

(Synonyms: Lasalocid-A; Ionophore X-537A; Antibiotic X-537A)

25999-31-9
Price and Availability of CAS No. : 25999-31-9
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5mg $60 In-stock
10mg $100 In-stock
25mg $180 In-stock
50mg $270 In-stock
100mg $390 In-stock
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Cat. No. : HY-B1071
M.Wt: 590.79
Formula: C34H54O8
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 25999-31-9 :

Lasalocid (Lasalocid-A) is an antibacterial and anticoccidial agent that can be used as feed additives. Lasalocid exhibits antitumor activity. Lasalocid is orally active[1][2][3]. In Vitro:Lasalocid (2.5 μg/mL) inhibits the growth of white spot bacteria, yellow spot bacteria, and fibrinolytic vibrio[1].
Lasalocid works in the rumen by selectively promoting the growth of succinate-producing Bacteroides and S. ruminantium, which can lead to an increased formation of propionate in the rumen[1].
Lasalocid (0-5 μM, 24-48 h) inhibits proliferations of cancer cells PC-3 and LNCaP, arrests the cell cycle at G0/G1 phase, induces apoptosis and autophagy in PC-3 cell[2].
In Vivo:Lasalocid (5-20 mg/kg/day, po, for 4 weeks) protects rats from Pneumocystis carinii-induced pneumonia[3].

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