CAS No. : 25999-20-6
(Synonyms: Lasalocid-A (sodium); Ionophore X-537A (sodium); Antibiotic X-537A (sodium))
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| Cat. No. : | HY-B1071A |
| M.Wt: | 612.77 |
| Formula: | C34H53NaO8 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Lasalocid sodium (Lasalocid sodium-A) is an antibacterial and anticoccidial agent that can be used as feed additives. Lasalocid sodium exhibits antitumor activity. Lasalocid sodium is orally active[1][2][3].
In Vitro:Lasalocid sodium (2.5 μg/mL) inhibits the growth of white spot bacteria, yellow spot bacteria, and fibrinolytic vibrio[1].
Lasalocid sodium works in the rumen by selectively promoting the growth of succinate-producing Bacteroides and S. ruminantium, which can lead to an increased formation of propionate in the rumen[1].
Lasalocid sodium (0-5 μM, 24-48 h) inhibits proliferations of cancer cells PC-3 and LNCaP, arrests the cell cycle at G0/G1 phase, induces apoptosis and autophagy in PC-3 cell[2].
In Vivo:Lasalocid sodium (5-20 mg/kg/day, po, for 4 weeks) protects rats from Pneumocystis carinii-induced pneumonia[3].
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