Cefazolin
CAS No. : 25953-19-9
(Synonyms: Cephazolin)
| Size | Price | Stock |
|---|---|---|
| 100mg | $60 | In-stock |
| 500mg | $180 | In-stock |
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| Cat. No. : | HY-B1892 |
| M.Wt: | 454.51 |
| Formula: | C14H14N8O4S3 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research[1]. Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD)[2].
IC50 & Target: Antibiotic[1]
In Vitro: Cefazolin (0-300 μg/ml; 6 or 24 h) has a direct anti-inflammatory effect on C8-B4 cells stimulated by lipopolysaccharide[2].
Cefazolin (0-400 μM; 72 h) treatment inhibits IL-2, IL-4 and IL-15-induced cell proliferation[3].
Cefazolin (100-400 μM; 30 min) treatment inhibits IL-2, IL-4, IL-15 and IL-21-stimulated JAK3 phosphorylation[3].
In Vivo: Cefazolin sodium pentahydrate (Subcutaneous injection; 300-500 mg/kg; once daily; 5 d) treatment improves learning and memory in mice after surgery[2].
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