LEP(116-130)(mouse)
CAS No. : 258276-95-8
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| Cat. No. : | HY-P1027 |
| M.Wt: | 1560.73 |
| Formula: | C64H109N19O24S |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic) |
LEP(116-130)(mouse) is a synthetic leptin peptide fragment. In Vitro: LEP-(116-130) (300 µM) is unable to inhibit AP-OB binding[1]. In Vivo: LEP-(116-130) (1 mg, i.p.) results in a reduced rate of body weight gain in the presence of increased food intake compared with vehicle-injcted control mice. LEP-(116-130) significantly reduces blood glucose levels by appr 100 mg/dL. Administration of LEP-(116-130) to wild-type (+/+) C57BLKS/J-m mice for 4 or 7 days has no effect on their ability to thermoregulate[1].
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