N-Desmethyl rosiglitazone


CAS No. : 257892-31-2

(Synonyms: SB 237216)

257892-31-2
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Cat. No. : HY-118788
M.Wt: 343.40
Formula: C17H17N3O3S
Purity: >98 %
Solubility:
Introduction of 257892-31-2 :

N-Desmethyl rosiglitazone (SB 237216) is a metabolite of Rosiglitazone (HY-17386), generated through demethylation by the cytochrome P450 enzyme system in liver microsomes. It retains partial PPARγ agonist activity and supports studies on the metabolism and pharmacokinetics of Rosiglitazone (HY-17386)[1].

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