CP 154526 (hydrochloride)
CAS No. : 257639-98-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $130 | In-stock |
| 10mg | $210 | In-stock |
| 25mg | $460 | In-stock |
| 50mg | $760 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-12129 |
| M.Wt: | 400.99 |
| Formula: | C23H33ClN4 |
| Purity: | >98 % |
| Solubility: |
CP 154526 hydrochloride is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (Ki = >10 μM). CP 154526 hydrochloride has anxiolytic activities[1][2].
In Vitro:CP 154526 hydrochloride displaces [125I][Tyr0]CRF from rat hippocampal CRF receptors (IC50 = 0.5 nM) and from pituitary CRF receptors (IC50 = 0.04 nM)[2].
In Vivo:CP 154526 (1-10 mg/kg; i.p.; once) hydrochloride exhibits signs of anxiolytic-like activity in the elevated plus-maze test in rats[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- CP 154526 (hydrochloride)
- Cat. No.:
- HY-12129
- Quantity:
Your information is safe with us.