Fast green FCF (free acid)
CAS No. : 25738-40-3
| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-D0914A |
| M.Wt: | 764.88 |
| Formula: | C37H36N2O10S3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Fast green FCF free acid is a dye that is acid-resistant. Fast Green FCF free acid inhibits α-synuclein aggregation, as well as Aβ, P2X4 receptor and TLR4/Myd88/NF-κB. Fast Green FCF free acid is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF free acid improves cognitive impairment, depression, relieves pain allergies, and promotes reproductive function[1][2][3][4][5][6][7][8][9].
In Vitro:Fast Green FCF free acid (molar ratios of HEWL/FCF free acid: 1 to 0.01-1 to 1, 10 days) free acid suppresses the generation of lysozyme fibrils in a concentration-dependent manner and exhibits disaggregating activity against the preformed/existing lysozyme fibrils[2].
Fast Green FCF (100 μg/mL-1 mg/mL) free acid inhibits synaptic activity in rat hippocampal interneurons, with half-maximum effective concentration of ~200 μg/mL (250 μM)[3].
Fast Green FCF (5-100 μM, 24 h) free acid inhibits α-synuclein aggregation, disassembles mature fibrils and protects against amyloid-induced neurotoxicity in PC12 cells[4].
Fast green FCF (molar ratios of Aβ40 to FGF of 3:1-1:3) free acid alleviates the cytotoxicity induced by Aβ40 fibrillogenesis in PC12 cells[5].
In Vivo:Fast Green FCF (100 mg/kg, i.p., 30 min prior to each trial) free acid attenuates Aβ-induced cognitive impairment in mice[5].
Fast Green FCF (10-100 mg/kg, i.p., once daily, 30 min before surgery) free acid prevents postoperative cognitive dysfunction via the downregulation of the P2X4 receptor in mice[6].
Fast Green FCF (100 mg/kg, i.p., daily for 7 days) free acid attenuates lipopolysaccharide-induced depressive-like behavior and downregulates TLR4/Myd88/NF-κB signal pathway in the mouse hippocampus[7].
Fast Green FCF (30-100 mg/kg, i.p., daily for 9 days) free acid alleviates pain hypersensitivity and down-regulates the levels of spinal P2X4 expression and pro-inflammatory cytokines in a rodent inflammatory pain model[8].
Fast Green FCF (0.017-0.041 gm per kg body weight, p.o., 42 days) free acid causes a significant decrease in testicular weight, tubular diameter, sperm density, and sperm motility[9].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Fast green FCF (free acid)
- Cat. No.:
- HY-D0914A
- Quantity:
Your information is safe with us.