UK-371804
CAS No. : 256477-09-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $210 | In-stock |
| 25mg | $360 | In-stock |
| 50mg | $540 | In-stock |
| 100mg | $800 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-101214 |
| M.Wt: | 385.83 |
| Formula: | C14H16ClN5O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 8.33 mg/mL (ultrasonic) |
UK-371804 is a urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM. IC50 & Target: Ki: 10 nM (uPA)[1] In Vitro: UK-371804 is able to inhibit exogenous uPA in human chronic wound fluid (IC50=0.89 μM). UK-371804 has its excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin)[1]. In Vivo: In a porcine acute excisional wound model, following topical delivery, UK-371804 is able to penetrate into pig wounds and inhibit exogenous uPA activity with no adverse effect on wound healing parameters. Concentrations of UK-371804 in the dermis are 41.8 μM[1].
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- UK-371804
- Cat. No.:
- HY-101214
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