δ-Tocotrienol


CAS No. : 25612-59-3

25612-59-3
Price and Availability of CAS No. : 25612-59-3
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1mg $50 In-stock
5mg $120 In-stock
10mg $190 In-stock
25mg $380 In-stock
50mg $570 In-stock
100mg $840 In-stock
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Cat. No. : HY-122778
M.Wt: 396.61
Formula: C27H40O2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 25612-59-3 :

δ-Tocotrienol is a Vitamin E in vegetables, fruits, seeds, nuts, grains and oils. Vitamin E has become well known for its role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection. In Vitro:δ-Tocotrienol (10-80 µM, 72 h) inhibits the proliferation of cancer cell CNE1, CNE2, EC109, HONE1, HCT116, and MCF-7[1].
δ-Tocotrienol (0-40 µM, 24 h) inhibits AP-1 and NF-κB signaling pathway, activates caspase-3/8/9, arrests the cell cycle at G0/G1 phases, induces apoptosis in human nasopharyngeal carcinoma cell CNE1[1].
In Vivo:δ-Tocotrienol (75 mg/kg, sc, single dose) exhibits anti-inflammatory effect against radiation-induced gastrointestinal injury in CD2F1 mouse models[2].

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