1,6,7-Trihydroxyxanthone
CAS No. : 25577-04-2
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| Cat. No. : | HY-N0992 |
| M.Wt: | 244.20 |
| Formula: | C13H8O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
1,6,7-Trihydroxyxanthone is a potent anticancer agent. 1,6,7-Trihydroxyxanthone inhibits cell proliferation and induces cell Apoptosis. 1,6,7-Trihydroxyxanthone decreases Bmi-1 expressio and increases the protein levels expression of P14, P16[1].
In Vitro:1,6,7-Trihydroxyxanthone (0-10 µg/mL; 0-72 h) inhibits cell proliferation in HepG2, Bel7404 cells[1].
1,6,7-Trihydroxyxanthone (5 µg/mL; 72 h) induces cell apoptosis in HepG2 cells[1].
1,6,7-Trihydroxyxanthone decreases Bmi-1 expressio and increases the protein levels expression of P14, P16[1].
1,6,7-Trihydroxyxanthone induces MiR-218 up-regulation in HepG2, Bel7404 cells[1].
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