Artemisone
CAS No. : 255730-18-8
(Synonyms: Artemifone; BAY 44-9585)
| Size | Price | Stock |
|---|---|---|
| 5mg | $350 | In-stock |
| 10mg | $550 | In-stock |
| 25mg | $846 | In-stock |
| 50mg | $1100 | In-stock |
| 100mg | $1431 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-19502 |
| M.Wt: | 401.52 |
| Formula: | C19H31NO6S |
| Purity: | >98 % |
| Solubility: | DMSO : 130 mg/mL (ultrasonic) |
Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM[1]. Artemisone is also a potent inhibitor of human CMV[2].
IC50 & Target: IC50: 0.83 nM (P. falciparum)[1]
In Vitro: Artemisone inhibits 3D7 and K1 P. falciparum, with IC50s of 0.88±0.59 and 1.23±0.64 nM, respectively[1].
In Vivo: Artemisone is effectve at inhibiting the parasitaemia in the P. berghei NY susceptible strain, with an ED50 of 9.62 mg/kg via subcutaneous route and 11.67 mg/kg via oral administration[1].
Artemisone (3, 1, 0.3 and 0.1 mg/kg, s.c.) in combination with ohter antimalarials has enhanced effect against the chloroquine-resistant line P. yoelii NS[1]
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