Poly-L-Glutamic acid (MW 700000)


CAS No. : 25513-46-6

25513-46-6
Price and Availability of CAS No. : 25513-46-6
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250mg $6 In-stock
1g $10 In-stock
5g $11 In-stock
10g $22 In-stock
25g $36 In-stock
100g $116 In-stock
500g $461 In-stock
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Cat. No. : HY-112111
M.Wt: 1000.00
Formula: (C5H9NO4)x
Purity: >98 %
Solubility: H2O : 100 mg/mL (ultrasonic)
Introduction of 25513-46-6 :

Poly-L-Glutamic acid (MW 700000) is a synthetic polypeptide with biocompatibility, biodegradability and non-immunogenicity. Poly-L-Glutamic acid is an ideal tumor-targeting polymer carrier. Poly-L-Glutamic acid can be hydrolyzed by cathepsin B during metabolic decomposition[1][2][3]. In Vitro:Poly-L-Glutamic acid acts as a covalent carrier for Paclitaxel (TXL) (HY-B0015) to form PG-TXL (CT-2103)[1].
Poly-L-Glutamic acid is used to construct targeted hybrid peptosomes co-loaded with Doxorubicin (HY-15142A) and USPIONs as a theranostic platform for metastatic breast cancer[3].

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