Fibrinopeptide A, human
CAS No. : 25422-31-5
(Synonyms: Human fibrinopeptide A)
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| Cat. No. : | HY-P1538 |
| M.Wt: | 1536.56 |
| Formula: | C63H97N19O26 |
| Purity: | >98 % |
| Solubility: | H2O |
Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain. In Vitro: The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively[1]. In Vivo: Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2].
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