Kanamycin (sulfate)
CAS No. : 25389-94-0
(Synonyms: Kanamycin A (sulfate))
| Size | Price | Stock |
|---|---|---|
| 200mg | $50 | In-stock |
| 1g | $60 | In-stock |
| 5g | $80 | In-stock |
| 10g | $128 | In-stock |
| 25g | $256 | In-stock |
| 50g | $410 | In-stock |
| 100g | $630 | In-stock |
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| Cat. No. : | HY-16566A |
| M.Wt: | 582.58 |
| Formula: | C18H38N4O15S |
| Purity: | >98 % |
| Solubility: | DMSO : < 1 mg/mL;H2O : ≥ 25 mg/mL |
Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia[1][2][3][4].
In Vitro: Kanamycin sulfate (0.1-100 μg/mL; 2 weeks) exhibits good antibacterial activity (MIC=1-5 μg/mL) to various strains of mycobacteria in vitro[1].
In Vivo: Kanamycin sulfate (2, 4 mg/kg; s.c.; once daily, 6 times a week for 3 weeks) inhibits growth of bovine tubercle bacilli in lung and spleen of mice[1].
Kanamycin sulfate (1.25, 5 mg/kg; s.c.; single (at 3 h after infection)) inhibits the multiplication of K. pneumonia DT-S in lung, trachea, and blood of mice and in proportion to the dose administration, and also increases the survival rate of mice[2].
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