Asperulosidic Acid


CAS No. : 25368-11-0

25368-11-0
Price and Availability of CAS No. : 25368-11-0
Size Price Stock
1mg $160 In-stock
5mg $350 In-stock
10mg $580 In-stock
25mg $950 In-stock
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Cat. No. : HY-N6246
M.Wt: 432.38
Formula: C18H24O12
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 25368-11-0 :

Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities[1]. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways[2]. In Vitro: Asperulosidic Acid (ASPA) (40-160 μg/mL; pre- 1 hour) significantly down-regulates the mRNA levels of TNF-α and IL-6 in LPS-induced RAW 264.7 cells compared with the group treated with LPS alone [1].
Asperulosidic Acid (ASPA) (40-160 μg/mL; pre- 1 hour) decreases IκB-α phosphorylation in a concentration-dependent manner, decreases Erk1/2 phosphorylation at all concentration levels, but there was no effect on p-p38 [1].

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