Apelin-36(human)


CAS No. : 252642-12-9

252642-12-9
Price and Availability of CAS No. : 252642-12-9
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5mg $1500 In-stock
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Cat. No. : HY-P1064
M.Wt: 4195.83
Formula: C184H297N69O43S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 252642-12-9 :

Apelin-36(human) is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. Apelin-36(human) shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC50=8.61). Apelin-36 has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ[1][2][3][4].

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