CP-547632 (hydrochloride)
CAS No. : 252003-71-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $85 | In-stock |
| 10mg | $125 | In-stock |
| 25mg | $220 | In-stock |
| 50mg | $310 | In-stock |
| 100mg | $435 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-13302B |
| M.Wt: | 568.86 |
| Formula: | C20H25BrClF2N5O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 60°C);H2O : < 0.1 mg/mL |
CP-547632 hydrochloride is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC50s of 11 nM and 9 nM, respectively. CP-547632 hydrochloride is selective for VEGFR2 and bFGF over EGFR, PDGFRβ, and related tyrosine kinases (TKs). CP-547632 hydrochloride has antitumor efficacy[1].
In Vitro: CP-547632 hydrochloride (1-1000 nM; 1 hours) inhibits VEGF-stimulated VEGFR-2 phosphorylation in a dose-dependent fashion, with an IC50 value of 6 nM[1].
In Vivo: CP-547632 hydrochloride (p.o.; 6.25-100 mg/kg/day; for 10-24 days) causes a dose-dependent inhibition of growth in Colo-205, DLD-1, and MDA-MB-231 xenografts[1].
CP-547632 hydrochloride (oral; 50 mg/kg; a single oral dose) yieldes plasma concentrations above 500 ng/ml for 12 hours[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- CP-547632 (hydrochloride)
- Cat. No.:
- HY-13302B
- Quantity:
Your information is safe with us.