Miriplatin (hydrate)
CAS No. : 250159-48-9
(Synonyms: SM-11355 (hydrate))
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| Cat. No. : | HY-16325 |
| M.Wt: | 782.01 |
| Formula: | C34H70N2O5Pt |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Miriplatin hydrate (SM-11355 hydrate) is a chemotherapy agent which belongs to the class of alkylating agents. In Vitro: Miriplatin suspended in lipiodol (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis[2]. In Vivo: Miriplatin (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells[1]. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells[2].
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