CLX-0921


CAS No. : 249886-47-3

249886-47-3
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Cat. No. : HY-19394
M.Wt: 519.57
Formula: C28H25NO7S
Purity: >98 %
Solubility:
Introduction of 249886-47-3 :

CLX-0921 is an orally active PPARγ agonist with an IC50 of 1.54 μM. CLX-0921 has a potent antihyperglycemic activity, and can be used for the study of type 2 diabetes[1]. In Vitro:CLX-0921 (0.01 M, 0.1 M, 1.0 M, and 10 M) increases glucose uptake in 3T3-L1 adipocytes. CLX-0921 has potent antihyperglycemic activity with low adipogenic potential[1]. In Vivo:CLX-0921 (3.1-12.5 mg/kg; oral gavage; once daily; for 19 days) shows dose-dependent antihyperglycemic activity[1].

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