Bisdemethoxycucurmin


CAS No. : 24939-16-0

(Synonyms: Curcumin III; Didemethoxycurcumin)

24939-16-0
Price and Availability of CAS No. : 24939-16-0
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5mg $50 In-stock
10mg $80 In-stock
25mg $150 In-stock
50mg $220 In-stock
100mg $330 In-stock
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Cat. No. : HY-N0007A
M.Wt: 308.33
Formula: C19H16O4
Purity: >98 %
Solubility: DMSO : 66.67 mg/mL (ultrasonic)
Introduction of 24939-16-0 :

Bisdemethoxycucurmin (Curcumin III) is a curcuminoid compound and an inhibitor of P-glycoprotein and ferroptosis. Bisdemethoxycucurmin exhibits multiple activities such as anti-oxidation, anti-inflammation and anti-tumor. Bisdemethoxycucurmin can be used for the research of tumors and inflammatory diseases[1][2][3]. In Vitro:Bisdemethoxycucurmin (24 h) inhibits lipid peroxidation in primary rat nucleus pulposus cells treated with TNF-α[1].
Bisdemethoxycucurmin (1-10 μg/mL; 4 h) is cytotoxic and inhibits DNA synthesis in human chronic myeloid leukemia cells[2]. In Vivo:Bisdemethoxycucurmin (72.5 μg; topical application; 7 times) exhibits antitumor activity in a mouse skin papilloma model[2].

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