4-Amino-3-methoxybenzoic acid


CAS No. : 2486-69-3

2486-69-3
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Cat. No. : HY-75577
M.Wt: 167.16
Formula: C8H9NO3
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 2486-69-3 :

4-Amino-3-methoxybenzoic acid is a substituted aminobenzoic acid chemical intermediate. 4-Amino-3-methoxybenzoic acid also serves as a building block for the synthesis of acylurea derivatives in studies on human liver glycogen phosphorylase inhibitors. 4-Amino-3-methoxybenzoic acid can be used in organic synthesis and medicinal chemistry research[1][2]. In Vitro:4-Amino-3-methoxybenzoic acid (compound 12) (0.05 M; 2-aminothiophenol: 0.053 M; PPA: 85 g; 220 °C; 4 h) serves as the acid component in PPA-mediated benzothiazole synthesis, yielding a mixture of 5 products[1].
4-Amino-3-methoxybenzoic acid reacts with the 2-chlorobenzoyl-derived intermediate to yield 4-[3-(2-chlorobenzoyl) ureido]-3-methoxybenzoic acid with a yield of 89%[2].
4-Amino-3-methoxybenzoic acid reacts with the 2,4-dichlorobenzoyl-derived intermediate to yield 4-[3-(2,4-dichlorobenzoyl) ureido]-3-methoxybenzoic acid with a yield of 99%[2].
4-Amino-3-methoxybenzoic acid reacts with the 2-fluorobenzoyl-derived intermediate to afford 4-[3-(2-fluorobenzoyl) ureido]-3-methoxybenzoic acid in a yield of 98%[2].
4-Amino-3-methoxybenzoic acid reacts with the 2-chloro-4-fluorobenzoyl-derived intermediate to afford 4-[3-(2-chloro-4-fluorobenzoyl) ureido]-3-methoxybenzoic acid with a yield of 97%[2].

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