6-Methoxy-2-naphthoic acid
CAS No. : 2471-70-7
(Synonyms: 6-MNA; Naproxen impurity O)
| Size | Price | Stock |
|---|---|---|
| 250mg | $5 | In-stock |
| 1g | $10 | In-stock |
| 5g | $19 | In-stock |
| 10g | $35 | In-stock |
| 25g | $66 | In-stock |
| 100g | $215 | In-stock |
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| Cat. No. : | HY-B2121 |
| M.Wt: | 202.21 |
| Formula: | C12H10O3 |
| Purity: | >98 % |
| Solubility: |
6-Methoxy-2-naphthoic acid (6-MNA) is the active metabolite of Nabumetone (HY-B0559). 6-Methoxy-2-naphthoic acid is also an inhibitor of COX-1 and COX-2. 6-Methoxy-2-naphthoic acid can inhibit the synthesis of gastric mucosal prostaglandin E2. 6-Methoxy-2-naphthoic acid can be used in the research of inflammation and pain-related diseases. In addition, 6-Methoxy-2-naphthoic acid is an impurity in Naproxen (HY-15030) and can also be used in the synthesis of other active compounds[1][2]. In Vitro:6-Methoxy-2-naphthoic acid (0-100 μM; 0-24 h) inhibits COX-1 and COX-2 with IC50 values of 31.01 μM and 19.84 μM, respectively (in human whole blood)[1].
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