NVP-DPP728


CAS No. : 247016-69-9

247016-69-9
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Cat. No. : HY-14292
M.Wt: 298.34
Formula: C15H18N6O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 247016-69-9 :

NVP-DPP728 is a potent, reversible and nitrile-dependent dipeptidyl peptidase IV (DPP-IV) inhibitor. NVP-DPP728 can inhibit human DPP-IV amidolytic activity with a Ki of 11 nM. NVP-DPP728 inhibits degradation of glucagon-like peptide-1 (GLP-1) and thereby potentiates insulin release in response to glucose intake. NVP-DPP728 can be used for researching diabetes[1]. IC50 & Target: Ki: 11 nM (DPP-IV)[1]

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