C16-Ceramide (d18:1/16:0)
CAS No. : 24696-26-2
(Synonyms: C16-Ceramide)
| Size | Price | Stock |
|---|---|---|
| 100mg | $232 | In-stock |
| 250mg | $413 | In-stock |
| 1g | $990 | In-stock |
| 5g | $3948 | In-stock |
| 10 g | Get quote | |
| 50 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-100354 |
| M.Wt: | 537.90 |
| Formula: | C34H67NO3 |
| Purity: | >98 % |
| Solubility: | Ethanol : 20 mg/mL (warming;heat to 60°C);DMF : 20 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : < 1 mg/mL (ultrasonic) |
C16-Ceramide (d18:1/16:0) is a natural small molecule activating p53 through the direct and selective binding[1].
IC50 & Target:p53[1], Apoptosis[2]
In Vitro: C16-Ceramide (d18:1/16:0) interacts with p53 within its core domain. p53 forms complex with natural C16-Ceramide (d18:1/16:0) in the cell[1].
C16-Ceramide (d18:1/16:0) (2.5-50 μM; 0-48 h) strongly decreased HCT116 cell viability in a time- and concentration-dependent manner[2].
C16-Ceramide (d18:1/16:0) (12 μM; 48 h) induces apoptosis through Btf (Bcl-2-associated transcription factor) in HCT116 cells[2].
C16-Ceramide (d18:1/16:0) (12 μM; 0-6 h) and Btf expression up-regulate p53 and BAX expression. C16-Ceramide (d18:1/16:0) down-regulates Mdm2 expression via Btf[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- C16-Ceramide (d18:1/16:0)
- Cat. No.:
- HY-100354
- Quantity:
Your information is safe with us.