Ro 64-5229
CAS No. : 246852-46-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $417 | Get quote |
| 10mg | $667 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-103557 |
| M.Wt: | 352.26 |
| Formula: | C17H19Cl2N3O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Ro 64-5229 is a selective, non-competitive mGlu2 antagonist. RO 64-5229 reduces the presynaptic inhibitory effect of Neuroligin 1[1].
IC50 & Target:mGlu2[1].
In Vitro:RO 64-5229 (50 µM) reduces the presynaptic inhibitory effect of NL1 (Neuroligin 1)[1].
RO 64-5229 (0.1, 0.3, 1 µM; 20 min) inhibits the inhibitory activity of neuroligin 1 ectodomain (Ecto-NL1; mGluR2 activator) on Forskolin (Ecto-NL1 decreases the Forskolin-induced formation of cAMP) in HEK-mGluR2 cells[1].
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