Lenperone (hydrochloride)
CAS No. : 24677-86-9
(Synonyms: AHR 2277)
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| Cat. No. : | HY-114682A |
| M.Wt: | 407.88 |
| Formula: | C22H24ClF2NO2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Lenperone hydrochloride (AHR 2277) is an antipsychotic compound and a dopamine antagonist. Lenperone hydrochloride reduces gastroesophageal sphincter pressure of healthy dogs. Lenperone hydrochloride can be used for neurological disease research[1][2]. In Vivo:Lenperone hydrochloride (0.16 and 0.44 mg/kg; intramuscular injection; once) decreases mean gastroesophageal sphincter pressure (GESP) of healthy dogs[1]. Lenperone hydrochloride (0.5, 1.0 and 2.0 mg/kg; subcutaneous injection) shows antipsychotic effects with inducing a dose-dependently cataleptic state and reducing bilateral lesion of the nucleus interstitialis stria terminalis in rats with brain damage[2].
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