Monoethyl fumarate


CAS No. : 2459-05-4

2459-05-4
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Cat. No. : HY-W019696
M.Wt: 144.13
Formula: C6H8O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic);H2O : 25 mg/mL (ultrasonic)
Introduction of 2459-05-4 :

Monoethyl fumarate is the monoethyl ester form of Fumaric acid (HY-W015883). Monoethyl fumarate is the activator for Nrf2. Monoethyl fumarate is a kind of effective preservative and polymerization agent for macromolecular material[1][2]. In Vitro:Monoethyl fumarate (1-6 μg/mL, 6-24 h) modifies the Cys151 site on the KEAP1 protein, modulates the glutathione expression, induces nuclear translocation of NRF2 protein, and the expression of NRF2 target genes[2].

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