RWJ52353


CAS No. : 245744-10-9

245744-10-9
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Cat. No. : HY-103216
M.Wt: 202.28
Formula: C11H10N2S
Purity: >98 %
Solubility:
Introduction of 245744-10-9 :

RWJ52353 is a selective, orally active ligand for α2D adrenoceptor, which binds α2D, α2A, α2B and α1 receptors, with Kis of 1.5, 254, 621 and 443 nM. RWJ52353 exhibits analgesic efficacy in mouse abdominal irritation test (MAIT), with an ED50 of 15.1 mg/kg[1].

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