Advantame (free acid)
CAS No. : 245650-17-3
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| Cat. No. : | HY-122351 |
| M.Wt: | 458.50 |
| Formula: | C24H30N2O7 |
| Purity: | >98 % |
| Solubility: |
Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K+ channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits[1][2][3].
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