CRX-526
CAS No. : 245515-64-4
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| Cat. No. : | HY-118984 |
| M.Wt: | 1319.72 |
| Formula: | C69H127N2O19P |
| Purity: | >98 % |
| Solubility: |
CRX-526 is a TLR4 antagonist that can block the interaction of lipopolysaccharide (LPS, HY-D1056) with the immune system, including preventing the expression of pro-inflammatory genes stimulated by LPS, as well as blocking the release of TNF-α induced by LPS. CRX-526 exhibits anti-inflammatory effects in two mouse models of colitis (namely, the dextran sodium sulfate-induced colitis model and the multidrug resistance gene 1a-deficient mouse model)[1].
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